Herpes Supplements: 15 Remedies to Manage HSV Outbreaks

For informational purposes only. Disclaimer. We occasionally link to affiliate products. Disclosure.

Fighting herpes is far easier when you’re proactive about your whole health. And if you know what to do when an outbreak strikes, you can beat it faster. Luckily, it doesn’t have to be hard. Looking for the best herpes supplements that work? It’s easy. This quick but complete guide will show you everything you need. Scroll down to get proactive.

photo of herbs and supplemental remedies

Herpes Supplements Guide

This is a complete list of natural herpes supplements. Some are almost always recommended by doctors for treatment of herpes viruses. Others? They have promising studies behind them, but need more research.

Note: This is about herpes supplements for cold sores or genital herpes related to HSV-1, HSV-2, and other herpes viruses. As always, check with your doctor to see what’s right for you.

1. Coconut Oil

Coconut oil has been in the spotlight for a few years now. But not just a trend, this superfood really does have proven health benefits.

Coconut Oil in jar

Virgin coconut oil has famous virus-fighting, free-radical-stopping, and bacteria-busting superpowers. This is mostly thanks to its high lauric acid content. Lauric acid is also found in mother’s milk, and boosts immunity.

To treat HSV with coconut oil, people apply it topically as well as eat it, or take it as a supplement. As long as it’s labeled as unrefined or virgin coconut oil, it has many uses for healing. It may help reduce or heal outbreaks.

Since virgin coconut oil is food, it is generally safe to use. Don’t worry, it doesn’t have a high argine-to-lysine ratio like coconut meat. It’s a fat, so it has no amino acids at all.

Coconut oil should be taken in a small amount each day, working up to a maximum dosage for your weight. This is usually between one and three tablespoons. It doesn’t take much: even a little bit can benefit you.

Get this Coconut Oil: Viva Coconut Oil ; MCT Oil

2. Lemon Balm

Lemon balm is a healing herb in the mint family. Botanists also call it Melissa officinalis, or just Melissa. It’s available as a tea, supplement, and oil.

It’s a popular remedy that has antiviral properties, and may show promise both as a herpes supplement and topical treatment.


  • A 2004 study tested the antiviral properties of lemon balm against herpes viruses. The authors suggested that lemon balm oil might be useful for topical treatment of herpes.1


Some people use a cotton swab with lemon balm oil or lemon balm extract dabbed onto the affected area. Some people report boiling the lemon balm tea leaves and making a compress of it to apply to outbreaks. Lemon balm creams are also available.

As a herpes supplement, people also take capsules or drink lemon balm tea. Some say this helps to cut back on outbreak frequency. Lemon balm is available as a tincture, oil, cream, a tea, or pill.

Try this: Lemon Balm Capsules ; Lemon Balm Tea ; Lemon Balm Salve

3. L-Lysine

Lysine is probably the most well-known supplement for managing herpes. Simply put, managing lysine levels in the diet helps you have fewer outbreaks. (Charts for lysine-arginine ratios in food)

Lysine is an amino acid you get from foods. Still, you can get it in supplement form.


  • Medical research shows that getting more lysine than arginine in your diet reduces outbreaks. Researchers believe this balance will even prevent outbreaks in times of stress, which is a major outbreak trigger. It may even diminish the severity of those flare-ups that do happen.
  • The University of Maryland Medical Center reports that based on multiple studies, lysine can reduce the number of oral herpes (cold-sores) outbreaks.

The key is to make sure you keep this balance all the time, and not just when you get an outbreak. Otherwise, it won’t work.


Supplements are an easy way to increase your lysine intake, but you don’t need a ton. All you have to do is keep your lysine levels higher than arginine. A dose of 500 to 1000 mg a day may be enough to put you in the right zone.

Lysine supplements that have minerals, such as bioflavonoids and zinc, as well as vitamins can work miracles to prevent and control herpes outbreaks.

Try this: ; Lysine with Zinc, Vitamin C and Vitamin B6

4. Monolaurin

If you know that coconut oil is good for you, then you’ll easily understand the benefits of monolaurin.

monolaurin or lauricidin bottle

Monolaurin is a concentrate of lauric acid, which is the compound that makes coconut oil so healthy. Lauric acid is even found in breast milk, and support babies’ immune systems. Otherwise, it is not common in nature.

Monolaurin has remarkable antiviral properties.


  • In vitro, it can destroy the lipid coating of viruses. For this reason, Monolaurin and coconut oil are both popular herpes supplements.

The lauric acid in monolaurin and coconut oil is also reported to boost immunity in general. In fact, it may be a good supplement for pregnant or breastfeeding mothers. As always, consult your doctor first.

Lauricidin is the only monoloaurin that has been clinically tested.

Get it here: Buy Real Lauricidin Monolaurin

5. Neem

Neem’s virus-fighting powers have earned it the nickname, “Nature’s Drugstore.” This herb has been used for centuries in Ayurvedic medicine.

neem plant

Fans of this plant take advantage of its health properties through use of the tree’s various products: neem oil, neem tea, or neem cream.


Typically, neem oil is used topically to relieve oral herpes (HSV-1) symptoms. With clean hands, a sufferer can apply it to the infected area with a q-tip or cotton swab at least once a day. People are also using this method to treat genital herpes.

Neem leaf can be used in neem tea to boost the immune system, which may also help with herpes outbreaks. The tea has a bitter taste but the primary reason people use it is for its medicinal qualities.

Neem can also be taken in a capsule form, or applied topically as a paste or an oil.

Does it work?

Anecdotes suggest that neem has worked for some people to reduce the severity of herpes outbreaks, but not get rid of them completely. It is also reported to relieve burning sensations when applied topically.

Precautions: Neem is not suitable for women who are pregnant, nursing, or trying to conceive. Some people may have allergic reactions to neem, although rare, and it may cause itching in some people.

Try these: Neem Tea ; Neem Capsules ; Neem Oil ; Organic Neem Butter

6. Olive Leaf

You may have heard of the Mediterranean diet. It’s known to improve health outcomes associated with aging. A large part of that diet is olives and olive oil.

olive leaf extract

Olive leaf extract offers those Mediterranean health benefits as well. It’s a popular and traditional remedy for many ailments: it boosts immunity, fights viruses, and may even have anticancer properties.

The main antioxidant in olive leaf extract is oleuropein. This compound may protect the brain, as well as protect against cancers.2  It has also been studied for its ability to inhibit viruses.


  • As for olive leaf extract for herpes, a 2007 study showed that the extract fights HSV-1 in test tubes.3
  • One private study showed that olive leaf extract tablets treated an outbreak more effectively than prescription acyclovir. (source needed)

Olive leaf is often cited not just as an oral or genital herpes supplement, but for all herpes viruses. Taking an olive leaf supplement can relieve outbreak sores, increase healing time, and restore energy levels from post-viral fatigue.


Typical dosage is 500mg tablets of olive leaf extract, one tablet every six hours, up to four per day. You can take these between meals for better absorption, though some sources say to take them with a meal. After a brief period this treatment may reduce sores.

One it’s working you can reduce your dosage until you are off the tablets to see if the herpes symptoms reappear. If it does, you can continue to use the olive leaf extract as long as you moderate the dosage. Ask your doctor what’s right for you.

Try this Olive Leaf Extract: Olive Leaf 20% Oleuropein Veggie Capsules

7. Resveratrol (Grapefruit Seed Extract)

Have you ever heard that red wine is good for you? Resveratrol is the good stuff you’re hearing about. It’s found in the skin of red grape seeds, berries, and even cocoa. It affects immune function, blood sugar levels, and improves cardiovascular health.

You commonly hear that it can extend lifespan and improve aging. But while it has improved lifespan in test subjects like insects, its effects for human lifespan appear to be unfounded, so far. Some fascinating animal and test tube benefits of resveratrol have been documented. But other benefits, like anticancer, diabetes, or skin benefits, are also not proven in humans and need further study.

What about using resveratrol for herpes?


  • Research in 2005 studied resveratrol in a cream applied to mice infected with HSV-1 and HSV-2. The authors found that a 19% resveratrol cream limited the reproduction of the virus vaginally in mice and reduced lesions.4
  • A 2006 study detailed how resveratrol could suppress HSV’s viral replication in vitro. The authors also noted effects of the compound on acyclovir-resistant strains of HSV-1.5

It is not documented in medical literature that taking a resveratrol supplement will have an antiviral effect on HSV. Nonetheless, it remains a popular supplement.

Precautions: A page on Oregon State’s website says pregnant women and women with a history of estrogenic cancers like breast cancer should avoid resveratrol supplements.

Where to Buy Resveratrol:  Best-Selling Extra-Strength Resveratrol

8. Red Marine Algae

Red marine algae is an abundant sea algae, with more than 4,000 species of it in the sea. It has been used for years in traditional Chinese medicine.

Specific types of red marine algae show strong immunity-boosting and antiviral properties. It is especially known for being effective for virus sufferers.

The first study showing the antiviral potential of marine algae was done in 1958.6 Polysaccharides derived from marine algae were shown to reduce the reproduction of enveloped viruses. The results were promising, and the potential continues to be researched today.

Today, the studies include herpes viruses:

  • A 2004 study published in Phytotherapy Research studied the antiviral properties of 70 species of marine life. The researchers found compounds from red marine algae to be one of the most effective. Using extracts from a type of red marine algae, the compounds inhibited HSV-1 and HSV-2 reproduction in in vero cell cultures.7
  • Research from 2011 focused on the possibilities of these marine compounds for pharmaceutical and nutraceutical uses. The cell walls of red algae are a rich source of carrageenans, the study says, which have antiviral potential.8
  • A 2012 study showed that specific red algae glycolipids were potent against HSV-1 and HSV-2. The researchers studied the effects on cell cultures. The authors noted that acyclovir achieved more, but the red algae was efficient for inhibiting stages of viral infection without creating drug-resistant strains.9
  • In addition to antiviral properties, carrageenans from red marine algae are also studied for antioxidant, anticoagulant, antitumor, and immunomodulatory effects.

Try this Red Marine Algae: Pure Planet Red Marine Algae Plus (With the potent Dumontiaceae, Gigartina strains of algae.)

9. Turmeric Extract (Curcumin)

Turmeric is a common ingredient in curries with a long history of use in ayurvedic medicine.


The active compound is curcumin. It’s an anti-inflammatory substance. For HSV, turmeric extract / curcumin makes your body cells less susceptible to viral infections.


  • A 1999 study published in the journal Antiviral Res studied curcumin’s effect on HSV-2 in vitro as well as in vivo in mice. The compound made viral particles of HSV-2 less infectious before infection of cells and mice genitals.10
  • In 2008, a study published in Virology reported that curcumin reduced infectiousness of HSV-1 in cellular cultures. The result suggested that curcumin has an effect on HSV’s immediate-early gene expression. However, it did not affect entry of the viral DNA into host cells. The researchers noted that curcumin slowed down replication of the HSV-1 virus.11


People use turmeric supplements, powdered turmeric, and turmeric extract. When selecting a supplement, note that nanoparticulate curcumin is more bio-available. To increase its availability, cook or dissolve it in oil.

Precautions: Turmeric and other natural remedies are not without side effects and needed precautions. Always consult your doctor before altering your diet or course of treatment. Turmeric should be avoided by the following individuals unless a doctor recommends its use: Those who are pregnant, Breastfeeding women, Those with gall bladder problems, Those with excess stomach acid, Those who will be undergoing any surgery, Those on anti-platelet or anti-coagulants

Get it Here: Turmeric Curcumin Veggie Caps

10. Vitamin A

Vitamin A is good for your immune health. Taken alongside Vitamin C and zinc, it can be effective for reducing outbreaks.

A University of Washington Study in 2000 suggested that a vitamin A deficiency can put women at an increased risk of contracting genital herpes. The results suggest that vitamin A improves immune health.

Sources of Vitamin A:

Excellent sources of vitamin A include foods such as beef liver, spinach, sweet potatoes, carrots and pumpkin. Cooked carrots are perhaps the best way to get this vitamin.

“Antiviral properties have been also attributed to vitamin A, vitamin C and zinc in combination, thought to result from enhancement of the immune responses against Herpes viruses.”


Adult needs of vitamin A is 900 mcg for men and 700 mcg for women. If one prefers to use vitamin A supplements rather than through the diet, the recommended daily intake for men is 6000 IU, and for women it’s 4000 IU.

Try this Vitamin A: Now Foods Vitamin A, 25000 IU

11. Vitamin B12

If you have herpes, what does stress do? It leads to outbreaks! Luckily, B vitamins are known for helping with stress and anxiety.

In fact, B12 and all B group vitamins are essential for wellness.


You can get your B group vitamins by taking a “Balanced B Complex” like this one. Foods high in Vitamin B12 are shellfish, skim milk, swiss cheese, and fortified cereals and soy products.

Try this Vitamin B Complex: B-Complex with Vitamin C Stress Formula

12. Vitamin C

You already know that Vitamin C is famous for colds. But did you know it could help fight herpes, too?

oranges in tree

According to Alan Gaby, a holistic medicine specialist, high Vitamin C can switch off the virus.

  • In the study, Dr Gaby recommends the intake of 10 ,000 mg of supplements daily to manage an active herpes outbreak and 500-3,000 mg daily to prevent future herpes outbreaks.

Note: Taking vitamin A, vitamin C and zinc in combination can especially enhance the immune response against herpes viruses.

Sources of Vitamin C:

Citrus fruits and juices are probably the first thing you think of. That’s true, but keep in mind the higher arginine content of orange juice. It’s important to get more lysine in your overall diet, so balance it out. Other sources are bell peppers, tomatoes, strawberries, leafy greens, broccoli, white and sweet potatoes, papaya, cantaloupe, watermelon, mango, winter squash, cauliflower, cabbage, blueberries, raspberries, cranberries, and pineapples.

Try this Vitamin C Supplement: Get the Best-Selling Vitamin C Here

13. Vitamin D

When you soak up some rays, your body makes Vitamin D. That’s good, because it’s an essential immunity booster. But with a herpes diagnosis, sunlight can sometimes be an outbreak trigger.

hiking in the sun

It’s not just people with HSV. Not getting enough vitamin D is a common problem. In fact, more than half of the population is deficient in Vitamin D.


  • A Japanese study showed that Vitamin D is more effective at preventing the flu than a vaccine. Vitamin D stimulates your immune system and rallies T cells to fight off infections.


To make sure you’re getting enough Vitamin D, get 10-15 minutes of sun exposure to day. If you’re sensitive to sunlight, or it’s still not enough, take a good Vitamin D supplement. You can also eat foods rich in Vitamin D, like mushrooms.

Try this Vitamin D Supplement: Vitamin D3 Softgels

14. Zinc

Zinc is an essential trace mineral. It strengthens the immune system and has medicinal uses for wound healing. It can heal sores, and is often recommended as a herpes supplement.

Low zinc levels can make a person more vulnerable to infection. However, zinc deficiencies are uncommon. People who may be deficient include elderly patients, people with highly restricted food intake, or those with Crohn’s disease or other absorption issues.


Zinc is shown to fight both HSV-1 and HSV-2 in in-vitro studies12. Small studies of human subjects have also shown promise for the topical use of zinc ointments and creams.

  • In the first study, cold sores treated with zinc oxide cream healed faster than those treated with a placebo.13
  • In a different study, subjects who used a formula of zinc oxide, l-lysine, and several other ingredients experienced fewer symptoms and shorter outbreaks.
  • A journal called “Alternative Medicine Review” published a 2005 finding that lysine and zinc together relieved oral herpes within six days.


Zinc is highly available in seafood like oysters, crab, and lobster. Beef and lamb are next. Seeds like sunflower, chia, and flax are also good sources.

You can get zinc in a multivitamin or take a zinc supplement. Since using it with lysine can make it more effective, some herpes supplements like i-lysine include zinc.

Precautions: Zinc should be taken in safe doses. Adults need 8 to 11 mg of zinc per day. Zinc may react with some antibiotics, and with cisplatin, a chemotherapy drug. Zinc can cause stomach upset and is not for an empty stomach, unless you buy a specialty formula. Make sure you get enough copper when taking zinc.

Zinc supplements: Solgar Chelated Zinc ; Lysine with Zinc, Vitamin C and Vitamin B6

Herpes Supplements Infographic

10 Supplements for herpes viruses infographic

Click here to shop for supplements for herpes simplex viruses / HSV.


  1. [1] http://www.sciencedirect.com/science/article/pii/S0944711308001128 [link]
  2. [2] Effects of the Olive-Derived Polyphenol Oleuropein on Human Health [link]
  3. [3] Motamedifar M, Nekoueian A, Moatari A. The Effect of Hydroalcoholic Extract of Olive Leaves against Herpes Simplex Virus Type 1. Iran J Med Sci. 2007;32:222–226. [link]
  4. [4] https://www.ncbi.nlm.nih.gov/pubmed/26693226 [link]
  5. [5] Resveratrol suppresses nuclear factor-kappaB in herpes simplex virus infected cells. https://www.ncbi.nlm.nih.gov/pubmed/16876885 [link]
  6. [6] Gerber, P., Dutcher, J., Adams, E., & Sherman, J. (1958). Protective effect of seaweed extracts for chicken embryos infected with influenza virus B or mumps virus. Proceedings of the Society for Experimental Biology and Medicine, 99, 590–593. [link]
  7. [7] Serkedjieva, J. (2004), Antiviral activity of the red marine alga Ceramium rubrum. Phytother. Res., 18: 480–483. doi:10.1002/ptr.1458 [link]
  8. [8] Kim, S. (2011). Medicinal Benefits of Sulfated Polysaccharides from Sea Vegetables. Carbohydrate Polymers, 84(1), 14-21. [link]
  9. [9] Souza, L.; Sassaki, G.; Romanos, M.; Barreto-Bergter, E. (2012). Structural Chracterization and Anti-HSV-1 and HSV-2 Activity of Glycolipids from the Marine Algae Osmundaria obtusiloba Isolated from Southeastern Brazilian Coast. Marine Drugs. [link]
  10. [10] Plant Products as topical microbicide candidates: assessment of in vitro and in vivo activity against herpes simplex virus type 2. Krystin Z. Bourne, Nigel Bourne, Shirley F. Reising, Lawrence R. Stanberry Volume 42, Issue 3, July 1999, Pages 219–22 [link]
  11. [11]  Curcumin inhibits herpes simplex virus immediate-early gene expression by a mechanism independent of p300/CBP histone acetyltransferase activity. Virology/ Vol. 373, Issue 2. 10 April 2008. Pages 239-247. Kutluay, Doroghazi, Roemer, Triezenberg [link]
  12. [12] Arens, M., & Travis, S. (2000). Zinc Salts Inactivate Clinical Isolates of Herpes Simplex Virus In Vitro. Journal of Clinical Microbiology, 38(5), 1758–1762. [link]
  13. [13] Godfrey HR, Godfrey NJ, Godfrey JC, Riley D. A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine. Altern Ther Health Med. 2001;7(3):49-56. [link]